Rovers head into Saturday’s clash at Sixfields Stadium without the influential Tom Anderson and uncertainty hanging over the fitness of two more defenders, Kyle Knoyle and Adam Long.
All three players limped off injured in last weekend's 2-1 win over Salford City, leaving Rovers to see out the match with a makeshift defence.
Injuries could provide an opportunity for young centre-half Bobby Faulkner to make his first professional start against the Cobblers.
Having turned 18 earlier this month, Faulkner impressed off the bench last time out and could fill in at either right-back in the centre of defence.
Here’s how we expect Doncaster to line up.
5. CB - Ro-Shaun Williams
Stepped up brilliantly last weekend when his colleagues went down one by one. Could be key this weekend. Photo: HOWARD ROE
6. CB - Adam Long
Feels like a close call between Long and Faulkner, provided the former is fit. He may edge it on his experience - which isn't far greater - and the fact his left foot would bring some balance to the defence. Photo: HOWARD ROE
7. CM - Adam Clayton
Another big shift last weekend from the skipper, who is in excellent form. Photo: HOWARD ROE
8. CM - Harrison Biggins
Put a shift in at right-back and in the middle of the park last weekend. Becoming a steady constant in the side. Photo: HOWARD ROE