Little Erin Moran’s family say they will fly to Frankfurt in Germany to pick up a trial drug they believe could help her, which she cannot get in the UK, after now deciding on the treatment to pursue.
The family understand the drug ONC201, has had greater success in shrinking the tumour and relieving symptoms than her present treatment, in some cases and hope it will prolong her life.
They are crowdfunding to pay for Erin's treatment.
So far the family, including dad Chris, 37, and oldest daughter Freya, 10 have raised £48,000.
Mum Nina Moran says Erin, from Campsall, was like any other little girl three months ago - before going to the doctor complaining of a squint in her eye.
Within two weeks her schoolgirl's speech became slurred and she was suffering pain in her right arm and leg, leading to more tests and an MRI.
On May 6, Erin was diagnosed with a rare brain tumour called diffuse intrinsic pontine glioma.
Since her diagnosis Erin's health has deteriorated. She can now no longer walk or feed herself without help.
Nina, who works as a nurse, said: "When Erin started feeling poorly we knew we were going to hear some bad news, but we never imagined anything like this.
"It was horrific, we didn't expect her to be so seriously ill.
"To hear it was horrific, it's not something you ever expect to hear as a parent.
"Since then Erin has deteriorated quite a lot, which is incredibly difficult to deal with."
"Despite everything Erin is still keeping her spirits up, she can have a laugh and enjoy herself."
The tumour attacks the brain stem affecting breathing, body temperature, heart rate, eye movements and swallowing.
Surgery is not possible in the UK because of its rarity, with only around 30 youngsters diagnosed in Britain each year.
Erin has undergone radiotherapy at Sheffield Children's Hospital, although it is still too early to tell how successful that treatment has been.
Donate to Erin by visiting: https://www.gofundme.com/f/pleasehelperinmoran?utm_medium=referral&utm_source=unknown&utm_campaign=comms_rtbm+PleasehelpErinMoran