The shop opens in Rowms Lane on Thursday, February 18, and will create 11 new jobs.
Store manager Mark Field said: “We’ve created 11 brand new vacancies and have employed local people from around the Swinton area.
“Our new team includes people of all ages and levels of experience, but the most important requirement is that they have the right attitude and can offer superb customer service.
“Everyone here is really looking forward to the store opening.”
Tradesmen and DIY fans are invited to attend the Swinton Screwfix opening where they can also demonstrate their professional skills in a free-to-enter screw drilling competition.