Wright missed last week's 1-1 draw at Peterborough United after suffering an ankle injury in training but has made a speedy recovery to face the Hatters.
He replaces Tom Anderson, who drops to the bench, in one of two changes from the trip to London Road.
Matty Blair has replaced skipper Tommy Rowe who is absent after suffering a hamstring injury in Tuesday's Checkatrade Trophy defeat to Newcastle United U21s.
Danny Andrew returns at left back - where Rowe started in midweek - following a foot injury while Niall Mason comes back in at right back after being rested.
James Coppinger is also back in the side after sitting out the Newcastle game.
Luton have made two changes from their 1-1 draw against Wycombe Wanderers from the previous week. In come forward Harry Cornick and midfielder Jorge Grant with James Justin and Andrew Shinnie dropping to the bench.
Rovers: Marosi; Mason, Wright, Butler, Andrew; Blair, Kane, Whiteman; Wilks, Marquis, Coppinger. Subs: Lawlor, T Anderson, Prior, J Anderson, Beestin, Taylor, May.
Luton: Shea, Stacey, Pearson, Bradley, Potts, Rea, Mpanzu, Grant, Lee, Cornick, Collins. Subs: Isted, Justin, McCormack, Shinnie, Jarvis, O'Kane, Sheehan.
Referee: Tom Nield (West Yorkshire)